Table 2 Univariate and multivariate Cox hazard analysis of risk factors for clinical outcomes of ALK + NSCLC patients

PFS

 CXCL9

1.8

1–3.1

0.045

0.85

0.41–1.7

0.65

 MIF

0.56

0.32–0.98

0.043

0.56

0.29–1.1

0.081

 IFNgamma

1.8

1–3.2

0.041

1

0.47–2.2

0.94

 CCL24

1.8

1–3.2

0.039

2.2

1.2–4.3

0.015

 IL6

1.9

1.1–3.3

0.029

1.2

0.54–2.7

0.65

 IL10

1.9

1.1–3.4

0.029

0.95

0.46–2

0.89

 CCL15

0.53

0.3–0.93

0.029

0.52

0.27–0.98

0.044

 CCL20

2.1

1.2–3.6

0.011

2.3

1.1–4.6

0.022

 CXCL13

2.1

1.2–3.7

0.0084

1

0.5–2.2

0.9

 IL8

2.2

1.2–3.9

0.0071

1.7

0.68–4.1

0.26

OS

 CCL24

2

1–4

0.043

1.8

0.89–3.6

0.1

 IL8

2.2

1.1–4.4

0.022

1.5

0.66–3.5

0.33

 CXCL13

2.7

1.3–5.4

0.0059

1.1

0.46–2.5

0.87

 CXCL9

2.6

1.3–5.2

0.0053

1.3

0.56–3.1

0.52

 IL6

2.7

1.3–5.3

0.005

1.6

0.66–4

0.29

 CCL20

3.1

1.5–6.1

0.0015

2.7

1.2–5.8

0.013