Fig. 2

Transcriptome analysis indicates that chemokines overexpression and angiogenesis are involved in crizotinib resistance. A Volcano plot of all differentially expressed genes (DEGs) between H3122 and H3122CR; B Top 30 Gene Oncology (GO) terms enriched among DEGs between H3122 and H3122CR; C Top 20 biological processes of DEGs from GSE94089; D Gene Set Enrichment Analysis (GSEA) of DEGs between H3122 and H3122CR; E The fold change of mRNA expression of chemokines in H3122CR compared to H3122