Fig. 4From: Enhanced immune activation within the tumor microenvironment and circulation of female high-risk melanoma patients and improved survival with adjuvant CTLA4 blockade compared to malesGene expression changes in female versus male patients. T-effector and IFNγ gene signature was higher in female tumors as compared to male tumors (P = 0.0244) There was a trend towards a higher score for the IFNγ 6-gene signature in favor of female (P = 0.07). On the otherhand, endothelial cells were estimated to be enriched in the tumors of male patients as estimated by TIMEx (P = 0.0429)Back to article page