An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure

Table 1 Significantly dysregulated metabolites quantified in human urinary EVs using LC–MS/MS

Metabolite	p-value	Fold change
Butyryl-coenzyme A	0.001	1.256
2-KetoHexanoic acid	0.004	0.781
Pantothenate	0.006	0.721
Lactate	0.008	0.834
2-phosphoglycerate	0.013	0.840
5-methyltetrahydrofolic acid	0.014	0.522
Xanthylic acid	0.038	0.763
Imidazole	0.040	0.837
dTTP	0.047	1.344
Flavin mononucleotide	0.047	0.807
Ethanolamine	0.048	0.892

List of metabolites that were significantly altered (p-value < 0.05) in human patient urinary EVs post-RT

ISSN: 1479-5876