Causal relationship between physical activity, leisure sedentary behaviors and COVID-19 risk: a Mendelian randomization study

Table 2 Sensitivity analysis of the causal association between leisure sedentary behaviors and the risk of COVID-19

Exposure	Outcome	Cochran Q test		MR-Egger		MR-PRESSO P value
Exposure	Outcome	Q value	P	Intercept	P	MR-PRESSO P value
MVPA	Susceptibility	5.37	0.50	0.009	0.29	0.70
	Hospitalization	17.08	0.31	− 0.008	0.73	0.33
	Severity	13.98	0.53	0.03	0.48	0.54
Accelerometer assessed PA	Susceptibility	11.77	0.70	0.002	0.86	0.52
	Hospitalization	17.52	0.008	0.02	0.59	0.69
	Severity	8.70	0.19	0.02	0.72	0.24
Accelerometer fraction of accelerations > 425 milligravities	Susceptibility	2.44	0.87	0.01	0.77	0.88
	Hospitalization	4.20	0.65	0.03	0.74	0.68
	Severity	11.86	0.07	− 0.07	0.77	0.08
Television watching	Susceptibility	78.90	0.12	0.0009	0.78	0.23
	Hospitalization	112.82	0.01	− 0.002	0.81	0.03
	Severity	90.33	0.04	− 0.002	0.88	0.02
Computer use	Susceptibility	21.95	0.34	0.006	0.46	0.35
	Hospitalization	21.63	0.36	0.03	0.12	0.38
	Severity	22.55	0.26	0.08	0.06	0.25
Driving	Susceptibility	116.22	0.01	− 0.006	0.78	0.70
	Hospitalization	1.45	0.69	− 0.05	0.43	0.69
	Severity	1.13	0.77	− 0.09	0.44	0.77

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