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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Identification of ISG15 and ZFP36 as novel hypoxia- and immune-related gene signatures contributing to a new perspective for the treatment of prostate cancer by bioinformatics and experimental verification

Fig. 1

Identification of hypoxia- and immune-related DEGs (DE-HRGs and DE-IRGs) in PCa. A The PCa patients of TCGA database were assigned to high- and low-hypoxia score groups based on optimal cut-off value of hypoxia score. B Kaplan–Meier (K–M) curve for disease-free survival (DFS) between high- and low-hypoxia score groups. C, D The volcano map and heatmap of DEGs between high- and low-hypoxia score groups. E, F The functional enrichment analysis of the DEGs between high- and low-hypoxia score groups based on KEGG and GO. G The PCa patients of TCGA database were assigned to high- and low-immune score groups based on optimal cut-off value of immune score. H Kaplan–Meier (K–M) curve for disease-free survival (DFS) between high- and low-immune score groups. I, J The volcano map and heatmap of DEGs between high- and low-immune score groups. K, L The functional enrichment analysis of the DEGs between high- and low-immune score groups based on KEGG and GO

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