Fig. 5

Inhibition of CAV1 facilitated albumin transcytosis in HK-2 cell. A Immunoblot of CAV1 and P-CAV1 in HK-2 after transfection with siCAV1 for 72 h. B Densitometric analysis of P-CAV1/CAV1 immunoblot signals (n ≥ 3). ^*P < 0.05 vs. NC. C Statistical FITC intensity in the upper chamber of Transwell (n ≥ 3). ^##P < 0.01 vs. NG + NC, ns vs. NG + NC, ^&&P < 0.01 vs. HG + NC. D FITC intensity in the lower chamber of Transwell (n ≥ 3). ^##P < 0.01 vs. NG + NC, ^**P < 0.01 vs. NG + NC, ^&&P < 0.01 vs. HG + NC. HG: high glucose; NC: normal control; NG: normal glucose