Table 2 Candidate genes in brain associated with stroke and stroke subtypes using TWAS
Stroke subtype | Gene | CHR | Z-score | P-value |
|---|---|---|---|---|
AS | ATXN2 | 12 | 4.805 | 1.55 × 10–6 |
|  | CDK6 | 7 | − 4.638 | 3.52 × 10–6 |
AIS | ATXN2 | 12 | 5.137 | 2.79 × 10–7 |
|  | NBEAL1 | 2 | 4.646 | 3.38 × 10–6 |
|  | CDK6 | 7 | − 4.463 | 8.08 × 10–6 |
LAS | – |  |  |  |
CES | SENP6 | 6 | − 4.751 | 2.03 × 10–6 |
|  | CAV1 | 7 | − 4.582 | 4.62 × 10–6 |
SVS | NBEAL1 | 2 | 5.286 | 1.25 × 10–7 |
|  | ICA1L | 2 | 5.109 | 3.24 × 10–7 |
|  | ALS2CR8 | 2 | 5.009 | 5.47 × 10–7 |