Fig. 10

Validation of DEPTH2 ITH in other datasets. A Kaplan–Meier curves showing that higher-DEPTH2-score (> median) tumors have worse survival than lower-DEPTH2-score (< median) tumors in multiple validation datasets. The log-rank test P-values are shown. OS: overall survival, DFS: disease-free survival. DEPTH2 scores having significant positive correlations with antitumor immune signatures (B) and tumor stemness scores (C) in multiple validation datasets. D DEPTH2 scores are significantly higher in high-grade than in low-grade tumors in 5 validation datasets