Table 1 Various indicators of participants and rats in the control (con) and diabetic nephropathy (DN) groups
From: The SETD8/ELK1/bach1 complex regulates hyperglycaemia-mediated EndMT in diabetic nephropathy
Human | |||
|---|---|---|---|
Variables | Con | DN | P-value |
Male (%) | 50 | 50 | 0 |
Age (years) | 51.3 ± 8.2 | 52.6 ± 9.0 | 0.83 |
BMI (kg/m2) | 22.5 ± 1.1 | 23.0 ± 3.3 | 0.35 |
SBP (mmHg) | 107.4 ± 16.3 | 144.9 ± 21.6 | < 0.0001 |
DBP (mmHg) | 61.2 ± 8.8 | 79.2 ± 12.6 | < 0.0001 |
HbA1C (%) | 5.2 ± 1.7 | 7.4 ± 0.7 | 0.0146 |
FBS (mmol/L) | 4.3 ± 1.1 | 9.5 ± 0.8 | < 0.0001 |
CREA (µmol/L) | 79.6 ± 26.7 | 227.8 ± 95.6 | < 0.0001 |
ALB (g/L) | 46.6 ± 9.4 | 30.6 ± 5.4 | 0.0049 |
CCr (mL/min) | 95.6 ± 8.7 | 54.9 ± 30.1 | < 0.0001 |
24 h UTP (mg) | 98.2 ± 10.1 | 3494.9 ± 1883.8 | < 0.0001 |
UA (µmol/L) | 187.3 ± 28.7 | 404.8 ± 83.3 | < 0.0001 |
TP (g/L) | 65.0 ± 4.7 | 52.1 ± 4.8 | 0.0008 |
Rats | |||
|---|---|---|---|
Variables | Con | DM | P-value |
Weight (g) | 356.9 ± 27.8 | 533.0 ± 41.1 | < 0.0001 |
Weight of kidney (g) | 1.6 ± 0.2 | 2.7 ± 0.7 | 0.0001 |
FBS (mmol/L) | 5.3 ± 0.8 | 11.6 ± 1.8 | < 0.0001 |
CREA (µmol/L) | 5.0 ± 1.1 | 11.6 ± 1.0 | < 0.0001 |
UREA (µmol/L) | 6.7 ± 0.6 | 11.5 ± 1.4 | < 0.0001 |
UMP (mg/L) | 115.8 ± 13.0 | 171.5 ± 11.0 | < 0.0001 |