Skip to main content

Table 2 Baseline characteristics of study participants and non-responders by common SNPs of GCKR genotypes

From: Evaluating machine learning-powered classification algorithms which utilize variants in the GCKR gene to predict metabolic syndrome: Tehran Cardio-metabolic Genetics Study

Variables

Male

Female

Responders (%)

Non-Responders (%)

P value

Responders (%)

Non-Responders (%)

P value

Group size (%)

2164 (72.28)

830 (27.72)

 

2590 (68.28)

1203 (31.72)

 

Age(mean ± SD)

39.35 ± 14.59

41.48 ± 15.31

0.06141

36.25 ± 11.51

37.06 ± 14.6

0.0649a

Schooling years (mean ± SD)

10.02 ± 4.65

9.91 ± 4.4

0.5821

9.58 ± 4.4

9.32 ± 4.36

0.145a

BMI (mean ± SD)

24.86 ± 3.87

25.12 ± 4.38

0.02461

26.31 ± 4.68

26.63 ± 4.92

0.0539a

Physical activity (mean ± SD)

607.79 ± 1049.11

524.49 ± 1034.92

0.05101

429.78 ± 696.21

384.48 ± 682.76

0.0607a

Smoking status (%)

 Never smoker

825 (38.12)

283 (34.10)

0.2212

1732 (66.87)

717 (59.60)

0.002b

 Former smoker

219 (10.12)

88 (10.60)

8 (0.31)

13 (1.08)

 Current smoker

547(25.28)

196 (23.61)

59 (2.28)

35 (2.91)

 Second hand

573(26.48)

171 (20.60)

791 (30.54)

371 (30.84)

Marital status (%)

 Divorced

12 (0.55)

1(0.05)

0.1042

33 (1.27)

18 (1.50)

 < 0.001b

 Married

1628 (75.23)

649(29.99)

2011 (77.64)

954 (79.30)

 Single

520 (24.03)

176 (8.13)

462 (17.84)

155 (12.88)

 Widowed

4 (0.18)

3 (0.14)

84 (3.24)

76 (6.32)

rs1260326 (%)

 CC

662 (30.59)

265 (31.93)

0.2332

755 (29.15)

370 (30.76)

0.602b

 TC

1015 (46.90)

402 (48.43)

1265 (48.84)

574 (47.71)

 TT

487 (22.50)

163 (49.64)

570 (22.01)

259 (21.53)

rs780094 (%)

 CC

676 (31.24)

251 (30.24)

0.302

773 (28.30)

358 (29.76)

0.998b

 TC

1015 (46.90)

414 (49.88)

1256 (48.49)

584 (48.55)

 TT

473 (21.86)

165 (19.88)

561 (21.66)

261 (21.70)

rs780093 (%)

 CC

672 (31.05)

179 (21.57)

0.1762

754 (29.11)

280 (23.28)

0.087b

 TC

1010 (46.67)

315 (37.95)

1275 (49.23)

404 (33.58)

 TT

482 (22.27)

125 (15.06)

561 (21.66)

214 (17.79)

  1. BMI Body Mass Index; There were no significant differences between responders and non-responders in males and females other than higher BMI and lower physical activity in male non-responders and different smoking and marital status distribution between female responders and non-responders
  2. aStudent's t-test
  3. bchi-square test
Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us