|
Variables
|
Male
|
Female
|
|---|
|
Responders (%)
|
Non-Responders (%)
|
P value
|
Responders (%)
|
Non-Responders (%)
|
P value
|
|---|
|
Group size (%)
|
2164 (72.28)
|
830 (27.72)
| |
2590 (68.28)
|
1203 (31.72)
| |
|
Age(mean ± SD)
|
39.35 ± 14.59
|
41.48 ± 15.31
|
0.06141
|
36.25 ± 11.51
|
37.06 ± 14.6
|
0.0649a
|
|
Schooling years (mean ± SD)
|
10.02 ± 4.65
|
9.91 ± 4.4
|
0.5821
|
9.58 ± 4.4
|
9.32 ± 4.36
|
0.145a
|
|
BMI (mean ± SD)
|
24.86 ± 3.87
|
25.12 ± 4.38
|
0.02461
|
26.31 ± 4.68
|
26.63 ± 4.92
|
0.0539a
|
|
Physical activity (mean ± SD)
|
607.79 ± 1049.11
|
524.49 ± 1034.92
|
0.05101
|
429.78 ± 696.21
|
384.48 ± 682.76
|
0.0607a
|
|
Smoking status (%)
|
|
Never smoker
|
825 (38.12)
|
283 (34.10)
|
0.2212
|
1732 (66.87)
|
717 (59.60)
|
0.002b
|
|
Former smoker
|
219 (10.12)
|
88 (10.60)
|
8 (0.31)
|
13 (1.08)
|
|
Current smoker
|
547(25.28)
|
196 (23.61)
|
59 (2.28)
|
35 (2.91)
|
|
Second hand
|
573(26.48)
|
171 (20.60)
|
791 (30.54)
|
371 (30.84)
|
|
Marital status (%)
|
|
Divorced
|
12 (0.55)
|
1(0.05)
|
0.1042
|
33 (1.27)
|
18 (1.50)
|
< 0.001b
|
|
Married
|
1628 (75.23)
|
649(29.99)
|
2011 (77.64)
|
954 (79.30)
|
|
Single
|
520 (24.03)
|
176 (8.13)
|
462 (17.84)
|
155 (12.88)
|
|
Widowed
|
4 (0.18)
|
3 (0.14)
|
84 (3.24)
|
76 (6.32)
|
|
rs1260326 (%)
|
|
CC
|
662 (30.59)
|
265 (31.93)
|
0.2332
|
755 (29.15)
|
370 (30.76)
|
0.602b
|
|
TC
|
1015 (46.90)
|
402 (48.43)
|
1265 (48.84)
|
574 (47.71)
|
|
TT
|
487 (22.50)
|
163 (49.64)
|
570 (22.01)
|
259 (21.53)
|
|
rs780094 (%)
|
|
CC
|
676 (31.24)
|
251 (30.24)
|
0.302
|
773 (28.30)
|
358 (29.76)
|
0.998b
|
|
TC
|
1015 (46.90)
|
414 (49.88)
|
1256 (48.49)
|
584 (48.55)
|
|
TT
|
473 (21.86)
|
165 (19.88)
|
561 (21.66)
|
261 (21.70)
|
|
rs780093 (%)
|
|
CC
|
672 (31.05)
|
179 (21.57)
|
0.1762
|
754 (29.11)
|
280 (23.28)
|
0.087b
|
|
TC
|
1010 (46.67)
|
315 (37.95)
|
1275 (49.23)
|
404 (33.58)
|
|
TT
|
482 (22.27)
|
125 (15.06)
|
561 (21.66)
|
214 (17.79)
|
- BMI Body Mass Index; There were no significant differences between responders and non-responders in males and females other than higher BMI and lower physical activity in male non-responders and different smoking and marital status distribution between female responders and non-responders
- aStudent's t-test
- bchi-square test
