Skip to main content

Table 4 Variant tissue-specific effects by eQTLs analysis on LPL gene

From: LPL, FNDC5 and PPARγ gene polymorphisms related to body composition parameters and lipid metabolic profile in adolescents from Southern Italy

SNPs

Alternative allele

p-value/NES

Thyroid

Adipose- Subcutaneous

Adipose Visceral (Omentum)

Whole blood

Kidney-cortex

Liver

rs4922115

A

3.5e−5/0.25

4.2e−4/0.07

0.08/0.05

1/2.4e−3

0.5/0.10

0.06/0.23

rs11570892

C

8.7e−7/0.25

5.3e−4/0.07

0.2/0.03

0.9/9.7e−3

0.5/0.10

0.06/0.23

rs3208305

T

8.9e−7/0.21

1.3e−7/0.09

3.2e−3 /0.06

3.1e−7/0.22

0.7/− 0.06

0.01/0.27

rs1059507

T

7.5e−7/0.26

3.1e−4/0.07

0.08/0.05

1/2e−3

0.5/0.10

0.08/0.22

rs3866471

A

3.7e−6/0.24

5.1e−4/0.07

0.1/0.04

0.5/0.03

0.5/0.10

0.09/0.21

  1. A p < 0.05 (marked in bold) was reported in the table indicating the existence of a relationship between a genetic variant and gene locus affecting gene expression in the analyzed tissue calculated by a T-statistics; NES indicates the normalized effect size across the tissues
Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us