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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Mini-XT, a miniaturized tagmentation-based protocol for efficient sequencing of SARS-CoV-2

Fig. 4

Mini-XT and Illumina sequencing results are comparable with those from Nanopore technology. Twenty samples with B.1.1.7 lineage were sequenced on both platforms. A The percentage coverage was very similar between platforms. B The same SNVs were identified by both platforms, as exemplified in a SnipIt plot of 10 pairs of sequences aligned to a reference Wuhan sequence modified to contain all invariant SNVs identified in these samples. C In a phylogenetic tree of all 20 samples the same samples (named according to protocol and sample number) clustered together, reflecting consistent SNV calling (branch lengths shown in nucleotide substitutions per site)

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