Table 2 Incidence and Hazard ratio for chronic fatigue syndrome and chronic fatigue syndrome-associated risk factors
Variable | Event | PY | Rate# | Crude HR (95% CI) | Adjusted HR& (95% CI) |
|---|---|---|---|---|---|
Mycobacterium tuberculosis infection | |||||
No | 567 | 186,546 | 3.04 | 1.00 | 1.00 |
Yes | 148 | 40,159 | 3.69 | 1.46 (1.04, 2.04)* | 1.23 (1.03, 1.47)* |
Age, year | |||||
≤ 34 | 50 | 31,553 | 1.58 | 1.00 | 1.00 |
35–49 | 104 | 45,185 | 2.30 | 1.46 (1.04, 2.04)* | 1.44 (1.02, 2.01)* |
50–64 | 174 | 55,869 | 3.11 | 1.99 (1.45, 2.72)*** | 1.90 (1.38, 1.60)*** |
65 + | 387 | 94,097 | 4.11 | 2.71 (2.01, 3.63)*** | 2.50 (1.86, 3.38)*** |
Sex | |||||
Female | 227 | 75,147 | 3.02 | 1.00 | 1.00 |
Male | 488 | 151,558 | 3.22 | 1.07 (0.92, 1.25) | – |
Comorbidity | |||||
Diabetes | |||||
No | 610 | 203,033 | 3.00 | 1.00 | 1.00 |
Yes | 105 | 23,672 | 4.44 | 1.53 (1.24, 1.88)*** | 1.20 (0.97, 1.49) |
Obesity | |||||
No | 710 | 224,949 | 3.16 | 1.00 | 1.00 |
Yes | 5 | 1756 | 2.85 | 0.93 (0.39, 2.24) | – |
Renal disease | |||||
No | 618 | 207,626 | 2.98 | 1.00 | 1.00 |
Yes | 97 | 19,079 | 5.08 | 1.76 (1.42, 2.18)*** | 1.41 (1.13, 1.76)** |
Rheumatoid arthritis | |||||
No | 715 | 226,313 | 3.16 | 1.00 | 1.00 |
Yes | 0 | 392 | 0.00 | – | – |
HIV | |||||
No | 714 | 226,474 | 3.15 | 1.00 | 1.00 |
Yes | 1 | 231 | 4.32 | 1.41 (0.20, 10.0) | – |
Malignancy | |||||
No | 693 | 221,075 | 3.13 | 1.00 | 1.00 |
Yes | 22 | 5630 | 3.91 | 1.30 (0.85, 1.99) | – |
Inflammatory bowel disease | |||||
No | 702 | 224,623 | 3.13 | 1.00 | 1.00 |
Yes | 13 | 2082 | 6.24 | 2.05 (1.19, 3.55)* | 1.83 (1.06, 3.17)* |