Fig. 2

UAP1L1 knockdown inhibited the prostate cancer cells apoptosis in vitro. A Flow cytometry was used to detect the cell apoptosis, and the results indicated that shUAP1L1 inducted the apoptosis of prostate cancer cells. B The intracellular signaling array after shUAP1L1 infection was determined. The red box indicated upregulation of proteins expression. C The expression of proteins associated with cell apoptosis pathway in shUAP1L1 group was compared to that in shCtrl group, and the fold change was also presented. D The proteins with signaling changes in expression levels were shown in histograms. ShCtrl: prostate cancer cells infected with shRNA of control; shUAP1L1: prostate cancer cells infected with shRNA of UAP1L1. *P < 0.05; **P < 0.01