Fig. 7

CircDYRK1A sponges miR-889-3p to promote FBXO4 expression. A The binding sites between miR-889-3p and FBXO4 predicted by starBase. B The expression of FBXO4 in GSE49051. C The expression of FBXO4 in GC tissues and adjacent normal tissues determined by RT-qPCR (n = 50). D The expression of FBXO4 in GC tissues and adjacent normal tissues determined by immunohistochemistry. E Pearson analysis of correlation between miR-889-3p and FBXO4. F Pearson analysis of correlation between circDYRK1A and FBXO4. G The correlation between miR-889-3p and FBXO4 detected by dual luciferase reporter assay. H The expression of FBXO4 in AGS and HGC-27 cells determined by RT-qPCR. The cell experiment was repeated three times. * p < 0.05