Fig. 7

Correlation between linc00261 and p-Smad3 in patient samples. A IHC analysis of p-SMAD3 protein expression in 35 human HCC tissues and paired normal tissues. B qRT-PCR analysis of relative linc00261 expression in the same 35 human HCC tissues and paired normal tissues. C High p-SMAD3 protein expression was associated with poor prognosis in human HCC patients. D Low linc00261 expression was associated with poor prognosis in human HCC patients. E Pearson correlation of linc00261 with p-SMAD3 protein in 35 human HCC tissues. F Schematic diagram of linc00261 induced inhibition of EMT and stemness in HCC cells. *** P < 0.001