Fig. 4
From: IRF-2 inhibits cancer proliferation by promoting AMER-1 transcription in human gastric cancer
The expression level of AMER-1 was positively related to IRF-2. A, B Western blotting and RT-PCR verified the positive relationship between IRF-2 and AMER-1 in both protein and mRNA levels, while the Wnt/β-catenin signaling pathway was negatively correlated with the IRF-2 and AMER-1 expressions in protein levels. C Immunohistochemical scores showed a positive correlation between AMER-1 and IRF-2 in tissue microarray. D A positive correlation between AMER-1 and IRF-2 was found in xenografted tumor tissues and a significant inverse correlation was also found between the expression of AMER-1 and CD44. E A positive correlation was also found between the expression of IRF-2 and AMER-1 on website GEPIA. *, P < 0.05; **, P < 0.005; ***, P < 0.0005