Fig. 2
From: IRF-2 inhibits cancer proliferation by promoting AMER-1 transcription in human gastric cancer
IRF-2 can affect GC cell proliferation both in vitro and in vivo. A Colony formation assays showed that colony formation ability was negatively correlated with IRF-2 expression. B CCK8 assays showed that the proliferation ability was inhibited by IRF-2. C EdU assays also showed that the GC cell proliferation ability was negatively correlated with IRF-2 expression. D In the xenograft tumor model, tumor volume increased in the IRF-2 knock down group