Interaction between a diabetes-related methylation site (TXNIP cg19693031) and variant (GLUT1 rs841853) on fasting blood glucose levels among non-diabetics

Table 4 Fasting blood glucose levels based on a combination of GLUT1 rs841853 genotypes and TXNIP cg19693031methylation quartiles

	β	p-value
GLUT1 rs841853 genotypes and TXNIP cg19693031 quartiles (ref: CC, ≥ Q3)
CC, Q2–Q3	0.7815	0.254
CC, Q1–Q2	1.7709	0.013
CC, < Q1	2.3116	0.001
CA + AA, > Q3	1.2367	0.117
CA + AA, Q2–Q3	− 0.1411	0.849
CA + AA, Q1–Q2	1.0363	0.152
CA + AA, < Q1	1.0330	0.167

GLUT1 glucose transporter 1, TXNIP thioredoxin-interacting protein, β: beta coefficient (denotes level of fasting blood sugar [mg/dL] for each category), ref: reference
Adjusted for sex, age, body mass index, cigarette smoking, alcohol drinking, triglyceride, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, hypertension, regular exercise, tea intake, coffee intake, and vegetarian diet

ISSN: 1479-5876