Fig. 5

Different TIME patterns and immunotherapeutic responses of LLPS subtypes. A Comparison of immune scores, stromal scores, ESTIMATE scores and tumor purity among LLPS subtypes. B Different proportion of high and low immunity tumors among LLPS subtypes. C, D The levels of immune cell infiltrations and immune functions quantified by ssGSEA Z-score among LLPS subtypes. E The proportion of 22 immune cells quantified by CIBERSORT algorithm among LLPS subtypes. F Comparison of immune checkpoint expressions among LLPS subtypes. G Comparison of TIDE scores among LLPS subtypes. H The proportion of ICI therapy responders predicted by TIDE algorithm among LLPS subtypes. I Comparison of MSI scores among LLPS subtypes. J Subclass mapping analysis for predicting the likelihood of response to ICI therapy of LLPS subtypes. * P < 0.05, ** P < 0.01, *** P < 0.001, and ^ns No significance