Fig. 3

The comparisons of demographics, clinicopathological features and cancer hallmarks among LLPS subtypes. A Comparisons of age, gender, KPS, survival status, histology, WHO grade, IDH status, MGMTp status and TERT status among LLPS subtypes. B Heatmap illustrated the ssGSEA Z-scores of 50 hallmarks among LLPS subtypes. Blue represented high scores, and yellow represented low scores. The obvious differences were highlighted by red box. C-D Volcano plots showed DEGs (P < 0.05 and |log₂FC|> 1.5) in LS1 and LS4 subgroups. E–F Gene Ontology enrichment analysis for significantly upregulated genes in LS1 and LS4, respectively. **P < 0.01, and ***P < 0.001