Skip to main content
Fig. 11 | Journal of Translational Medicine

Fig. 11

From: piRNA-14633 promotes cervical cancer cell malignancy in a METTL14-dependent m6A RNA methylation manner

Fig. 11

piRNA-14633 promotes CC progression by way of m6A RNA methylation. piRNA-14633 is overexpressed in cervical cancer. piRNA-14633 interactes with 3’UTR of METTL14 to increase METTL14 mRNA stability and promoted the methylase activity of METTL14 promoting the m6 A methylation levels of the downstream target (CYP1B1) and subsequently enhanced expression of CYP1B1, thereby contributed to tumorigenesis of CC

Back to article page