Journal of Translational Medicine

Table 2 Relationship between clinicopathological features and NUP37 or MCM2 expression in HCC patients (n = 300)

From: Demethylation at enhancer upregulates MCM2 and NUP37 expression predicting poor survival in hepatocellular carcinoma patients

Variable	NUP37				MCM2
Variable	Low	High		p-value	Low	High	p-value
Tumor size
≤ 5.6 cm	144	69		0.552	151	62	0.176
> 5.6 cm	55	32		0.552	54	33	0.176
T-stage
T1/T2/T3	177	92		0.707	184	85	1.000
T4	22	9		0.707	21	10	1.000
N-stage
N0	195	96		0.172	198	93	0.799
N1/Nx	4	5		0.172	7	2	0.799
M-stage
M0	195	94		0.039	197	92	1.000
M1	4	7		0.039	8	3	1.000
Age (year)
≤ 70	167	85		1.000	172	80	0.946
> 70	32	16		1.000	33	15	0.946
Gender
Female	28	11		0.554	29	10	0.495
Male	171	90		0.554	176	85	0.495
AFP (ng/ml)
≤ 500	156	77		0.782	156	77	0.418
> 500	43	24		0.782	49	18	0.418
ALT (U/L)
≤ 40	131	64		0.768	135	60	0.745
> 40	68	37		0.768	70	35	0.745
AST (U/L)
≤ 60	154	78		0.957	159	73	1.000
> 60	45	23		0.957	46	22	1.000

HCC, hepatocellular carcinoma; AFP, α-fetoprotein; ALT, alanine aminotransferase; AST, aspartate aminotransferase

Back to article page

ISSN: 1479-5876

Contact us

Submission enquiries: Access here and click Contact Us
General enquiries: info@biomedcentral.com