Fig. 1
From: Downregulation of NEDD4L by EGFR signaling promotes the development of lung adenocarcinoma
Expression and prognostic analysis of NEDD4L in LUAD. A The volcano plot for differentially expressed genes (DEGs) (FC > 1.5 and adjusted p-value < 0.05). B Relative mRNA level of NEDD4L in normal and tumor tissues from the TCGA_LUAD dataset. C Meta-analysis of NEDD4L using the Oncomine database showed that NEDD4L was significantly downregulated in LUAD tissues. D Representative IHC staining of NEDD4L in carcinoma and para-carcinoma tissues. E Relative protein levels of NEDD4L in carcinoma and para-carcinoma tissues. F–H Kaplan–Meier curves of the OS of the patients from the TCGA_LUAD, GSE68465, and GEPIA_LUAD database