Table 2 Number of SNPs identified from GWAS at different thresholds
P-value threshold | Number of significant SNPs identified from GWAS under the threshold | Number of SNPs after LD pruning | Number of SNPs mapped to external IBD GWAS and used in the PRS calculation | |
|---|---|---|---|---|
1 | 5 × 10–2 | 63,590 | 21,748 | 9620 |
2 | 5 × 10–3 | 5501 | 1104 | 471 |
3 | 5 × 10–4 | 442 | 72 | 33 |