From: FOXA1 can be modulated by HDAC3 in the progression of epithelial ovarian carcinoma
Parameter | Relapse | P value a | P value b | DOD | P value c | P value d | |||
---|---|---|---|---|---|---|---|---|---|
+ | − | + | − | ||||||
Age | |||||||||
< 57 | 24 | 28 | 0.172 | – | 17 | 41 | 0.240 | – | |
≥ 57 | 37 | 26 | 26 | 41 | |||||
FIGO staging system | |||||||||
I–II | 9 | 34 | < 0.001 | < 0.001 | 6 | 37 | 0.002 | 0.1 | |
III–IV | 52 | 20 | 37 | 45 | |||||
Lymphatic metastasis | |||||||||
No | 31 | 43 | 0.001 | 0.595 | 23 | 53 | 0.169 | – | |
Yes | 29 | 10 | 20 | 27 | |||||
HDAC3 H-score | |||||||||
Low expreesion | 19 | 40 | < 0.001 | 0.008 | 9 | 52 | < 0.001 | < 0.001 | |
High expression | 42 | 14 | 34 | 30 | |||||
FOXA1 H-score | |||||||||
Low expression | 23 | 35 | 0.001 | 0.853 | 14 | 46 | 0.006 | 0.951 | |
High expression | 38 | 19 | 29 | 36 |