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Table 2 Side effects occurring during ketogenic phase

From: VLCKD: a real time safety study in obesity

Parameters

N (%)

Time to onset from the beginning of VLCKD ± SD (days)

Duration (mean ± SD) (days)

Medically treated N (%) and which remedy N (%)

Headache

48 (45.3)

4.23 ± 4.99

7.43 ± 8.84

19 (17.9)9 (47.36) ibuprofen

9 (47.36) paracetamol

1 (5.26) indomethacin

Dry mouth

41 (43.5)

3.83 ± 3.22

19.95 ± 10.35

Dizziness

17 (16)

6.12 ± 7.26

9.35 ± 7.37

Hypotension

19 (17.9)

4.68 ± 4.69

11.31 ± 10.99

Visual disturbances

5 (4.7)

5.40 ± 4.72

8 ± 5.43

Low blood sugar

1 (0.9)

2

1

Lethargy

49 (46.2)

4.66 ± 4.40

15.9 ± 9.6

Halitosis

49 (46.2)

2.90 ± 1.52

22.06 ± 8.24

18 (17)

15(83.33) chewing gum

2 (11.11) oral spray

1 (5.55) mouthwash

Diarrhoea

13 (12.3)

13.31 ± 11.48

10.08 ± 11.48

Constipation

30 (28.3)

11.2 ± 16.20

16.37 ± 8.95

8 (7.5)

8 (100) osmotic laxative

Vomiting/nausea

16 (15.1)

4.81 ± 4.94

4.19 ± 3.25

2 (1.9)

1 (50) metoclopramide

1 (50) antacid

Hyperuricemia

11 (10.4)

8 (7.5)

8 (100) allopurinol

Urolithiasis

0

Gallbladder disease

0

Hair loss

16 (15.1)

15 ± 9.75

15 ± 20.19

3 (2.8)

3 (100) hair supplement

  1. Data are expressed as mean ± SD or n (%)