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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: Analysis and validation of m6A regulatory network: a novel circBACH2/has-miR-944/HNRNPC axis in breast cancer progression

Fig. 8

Up-expression of circBACH2 reversed the inhibitory effects of has-miR-944 on the proliferation of BC cells. qRT-PCR analysis of HNRNPC expression in MDA-MB-231 cell (A) and MCF-7 cell (B) after transfection with si-circBACH2 alone, has-miR-944 inhibitor alone and si-circBACH2 + has-miR-944 inhibitor group. C Western blot analysis of HNRNPC expression in MDA-MB-231 and MCF-7 cells after transfection with si-circBACH2 alone, has-miR-944 inhibitor alone and si-circBACH2 + has-miR-944 inhibitor group. The CCK8 assay (D) and the EdU assay (E) indicated the proliferation of MDA-MB-231 cells after transfection with si-circBACH2 alone, has-miR-944 inhibitor alone and si-circBACH2 + has-miR-944 inhibitor group. The CCK8 assay (D) and the EdU assay (E) indicated the proliferation of MCF-7 cells after transfection with si-circBACH2 alone, has-miR-944 inhibitor alone and si-circBACH2 + has-miR-944 inhibitor group. *P < 0.05 vs. siRNA negative control

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