Fig. 4

The differential taxa at the genus level between the paired thyroid cancer tissues and peritumor tissues from 30 patients with thyroid cancer. A Differential taxa at the genus level identified by linear discriminant analysis (LDA) effect size (LEfSe) analysis (LDA > 3.0, corrected P value < 0.05). B Differential taxa at the genus level identified by the random forest analysis. C–G The differential abundance of the 5 discriminative genera between 30 thyroid cancer tissues and matched peritumor tissues was further validated using the Mann–Whitney U test