Fig. 7

IL4I1 was a carcinogenesis gene in OC. A The mRNA expression level of IL4I1 was higher in OCs than paired normal samples. B Representative protein expression level of IL4I1 was high in OCs based on the Human Protein Atlas database. C Kaplan–Meier curve illustrating higher IL4I1 accompanied by poor OS. D Functions of IL4I1 with GSEA in OC. E Expression of MMP2, MMP9 were lower in siIL4I1 cells in protein level. F Downregulation of IL4I1 slow downed OC cell lines proliferation. G siIL4I1 significantly inhibited wound closure compared to the corresponding controls. Migratory (H) and invasive (I) cells were dramatically reduced in OC cells transfected with siIL4I1