Fig. 4
Viral DNA levels in tissues corresponding to visualized productive HIV-1 infection sites in Fig. 2. The first column in each panel represents tissue samples from infected mice; the second column represents tissues from HIV-1 infected, but cART treated mice; and the third column represents tissues from uninfected mice. The first panel is from LN, the second panel from liver, the third panel from brain, and the fourth panel from spleen tissues. The data include groups of 3 animals for the HIV-1 positive group, and 5 different animals for the HIV-1 positive, cART treated group and the HIV-1 negative control group. P values are 0.041, 0.001, < 0.001, and < 0.001 respectively, with the red lines indicating the average value of 3 or 5 mice per group. Copy numbers are graphed on a log10 scale and reported as copies per 106 human cells. *p < 0.05, **p < 0.01, ***p < 0.001