Fig. 1

FBXO43 was highly expressed in human breast cancer and was inhibited by lentiviral infection with shRNA against FBXO43. A FBXO43 expression levels in human breast invasive carcinoma and adjacent normal tissues according TCGA analysis. B FBXO43 expression levels in human breast cancer cell lines according to RT-qPCR. C FBXO43 expression levels in MDA-MB-231 cells infected with lentivirus containing shRNA against FBXO43 and negative control lentivirus according to western blot analysis and the quantitative analysis. D mRNA expression levels of FBXO43 in infected MDA-MB-231 cells according to RT-qPCR. All experiments were performed at least three times. NC negative control, KD FBXO43 knockdown. *P < 0.05, **P < 0.01, ***P < 0.001