Fig. 6From: MiR-144-3p inhibits gastric cancer progression and stemness via directly targeting GLI2 involved in hedgehog pathwayGLI2 reverses miR-144-3p-mediated suppression in gastric cancer. a The protein expression of GLI2 in HGC-27 that co-transfected miR-144-3p mimics and GLI2 overexpression (OE-GLI2) plasmid. b, c Clone formation of HGC-27 and clone number was counted. d The proliferation of HGC-27 was determined by CCK-8 assay. e, f Migration and invasion of HGC-27 was detected by Transwell assay and the migrated and invaded cells were counted. g The protein expression of GLI2 in SGC-7901 that co-transfected miR-144-3p inhibitor and GLI2 shRNA (shGLI2) plasmid. h, i Clone formation of SGC-7901 and clone number was counted. j The proliferation of SGC-7901 was determined by CCK-8 assay. k, l Transwell assay was performed to detect the migration and invasion of HGC-27 and the cells were counted. (*p < 0.05, **p < 0.01, ***p < 0.001)Back to article page