Skip to main content

Table 2 Regional brain gray matter density (mean ± SE, mm3/voxel) of CF patients and control corrected for age and sex

From: Regional brain tissue changes in patients with cystic fibrosis

Brain areas CF (n = 5) Controls (n = 15) p-values
Mean ± SE (95% confidence interval) Mean ± SE (95% confidence interval)
L Prefr Cor 0.44 ± 0.013 (0.42–0.47) 0.38 ± 0.007 (0.37–0.40) 0.001
R Prefr Cor 0.47 ± 0.012 (0.44–0.49) 0.41 ± 0.007 (0.40–0.43) 0.001
R Vent Med Prefr Cor 0.57 ± 0.012 (0.54–0.59) 0.52 ± 0.006 (0.50–0.53) 0.002
L basal forebrain 0.49 ± 0.011 (0.47–0.52) 0.44 ± 0.006 (0.42–0.45)  < 0.001
R basal forebrain 0.45 ± 0.012 (0.43–0.48) 0.39 ± 0.007 (0.38–0.41) 0.001
R amygdala 0.38 ± 0.009 (0.36–0.40) 0.34 ± 0.005 (0.33–0.35) 0.001
R hippocampus 0.71 ± 0.006 (0.70–0.72) 0.68 ± 0.003 (0.68–0.69) 0.002
R parahippocampus 0.59 ± 0.007 (0.57–0.60) 0.55 ± 0.004 (0.54–0.56)  < 0.001
R cerebellar Cor 0.75 ± 0.010 (0.73–0.77) 0.70 ± 0.005 (0.69–0.71) 0.001
L insula 0.63 ± 0.015 (0.60–0.66) 0.56 ± 0.008 (0.55–0.58) 0.001
R insula 0.61 ± 0.013 (0.59–0.64) 0.55 ± 0.007 (0.54–0.57) 0.001
L mid frontal Cor 0.60 ± 0.007 (0.58–0.61) 0.55 ± 0.004 (0.55–0.56)  < 0.001
L sup frontal Cor 0.62 ± 0.011 (0.60–0.64) 0.57 ± 0.006 (0.55–0.58) 0.001
L sup parietal Cor 0.69 ± 0.019 (0.65–0.73) 0.61 ± 0.010 (0.58–0.63) 0.002
R sup parietal Cor 0.59 ± 0.016 (0.56–0.63) 0.51 ± 0.009 (0.49–0.53) 0.001
R sup temp Cor 0.67 ± 0.008 (0.65–0.69) 0.63 ± 0.005 (0.62–0.64) 0.001
  1. CF cystic fibrosis, SE standard error, L left, Prefr prefrontal, Cor cortex, R right, Vent ventral, Med medial, Mid middle, Sup superior, Temp temporal