Fig. 4

CENPA promoted the proliferation, migration and invasion of ccRCC cells. CENPA A, B mRNA (n = 3 per group) and C protein levels were verified by qRT-PCR in A498 and Caki-1 cells with transient CENPA knockdown or overexpression. D–F Cell viability of A498 and Caki-1 cells after depleting or overexpressing CENPA was calculated using CCK-8 assays for four days (n = 6 per group). H The cell migration and invasion ability of transfected A498 and Caki-1 cells were evaluated using transwell assays (Magnification: 200×, n = 3 per group). *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. Error bars indicate mean ± SD