Feasibility and utility of MRI and dynamic 18F-FDG-PET in an orthotopic organoid-based patient-derived mouse model of endometrial cancer

Table 2 Mean values, range and 95% confidence intervals (CI) for ¹⁸F-FDG-PET and MRI tumor parameters during tumor progression

	SUV_max	SUV_mean	MTV (mm³)	TLG (SUV_mean x MTV)	MR_FDG (μmol/min)	ADC_mean (10³ mm²/s)	vMRI (mm³)
Scans	26	26	26	26	24	9^a	32
Mean	3.9	2.2	389	847	0.39	1.07	519
Range [min, max]	[2.1–5.2]	[1.5–2.8]	[49–1271]	[73–2389]	[0.12–0.61]	[0.86–1.48]	[2–1707]
95% CI [lower, upper]	[3.7–4.2]	[2.1–2.3]	[263–515]	[585–1108]	[0.34–0.45]	[0.94 -1.20]	[355–684]

CI confidence interval, SUV standardized uptake value, MTV metabolic tumor volume, TLG total lesion glycolysis, MR_FDG metabolic rate of fluorodeoxyglucose (obtained from dynamic imaging), vMRI anatomic tumor volume from MRI, ADC apparent diffusion coefficient
^aIncludes the four scans from the control mice from the treatment study

ISSN: 1479-5876