Table 4 Univariate and multivariate Cox regression analysis of second 3 point decrease of QMGS
Parameters | Univariate | Multivariate | ||
|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
Sex | ||||
Male | Ref. | – | ||
Female | 1.11 (0.87 to 1.41) | 0.398 | ||
Age, years | ||||
< 42 | Ref. | – | Ref. | – |
≥ 42 | 0.52 (0.40 to 0.66) | < 0.001 | 0.53 (0.41 to 0.68) | < 0.001 |
Disease course, months | ||||
< 8 | Ref. | – | ||
≥ 8 | 0.85 (0.67 to 1.07) | 0.164 | ||
Preoperative steroids | ||||
No | ref | – | ||
Yes | 0.94 (0.74 to 1.20) | 0.622 | ||
MGFA class | ||||
I + IIA | Ref. | – | Ref. | – |
IIB–V | 0.74 (0.57 to 0.96) | 0.025 | 0.79 (0.61 to 1.03) | 0.087 |
Surgical approach | ||||
Sternotomy | Ref. | – | ||
VATS | 1.12 (0.75 to 1.67) | 0.577 | ||
Masaoka-Koga stage | ||||
I | Ref. | – | Ref. | – |
IIa–IIIa | 0.51 (0.32 to 0.80) | 0.004 | 0.53 (0.33 to 0.84) | 0.007 |
WHO pathologic type | ||||
A + AB | Ref. | – | ||
B1–B3 | 1.23 (0.87 to 1.74) | 0.237 | ||
Tumor size | ||||
≤ 5 cm | Ref. | – | Ref. | – |
> 5 cm | 0.67 (0.45 to 0.98) | 0.042 | 0.92 (0.61 to 1.39) | 0.705 |
Complete resection | ||||
No | Ref. | – | Ref. | – |
Yes | 22.08 (2.03 to 240.48) | 0.011 | Failed estimationa | – |