Fig. 4

UBE2T augment cisplatin-induced autophagy. A Western blotting analysis was used to examine the effects of cisplatin treatments on autophagy in the A549 cells, followed by quantification using Image J (B). C Cisplatin-induced autophagy was further enhanced in the UBE2T overexpressing A549 cells, followed by quantification using Image J D. GAPDH was used as internal controls. E UBE2T overexpression decreased the sensitivity of A549 cells to cisplatin. F Autophagy inhibitor increased A549 cell’s sensitivity to cisplatin. All experiments were repeated at least three times. *P < 0.05, **P < 0.01, ***P < 0.001