Table 1 The baseline information of patients with colorectal cancer (CRC) and scoring interferon regulatory factor (IRF) family by random forest algorithm from The Cancer Genome Atlas (TCGA) database of COAD/READ datasets
| Patients from COAD/READ |
All patients (n = 597) |
Low (n = 298) |
High (n = 299) | P value |
|---|---|---|---|---|
| Gender | 0.904 | |||
| Female | 277 (46.4%) | 139 (46.6%) | 138 (46.2%) | |
| Male | 320 (53.6%) | 159 (53.4%) | 161 (53.8%) | |
| Age | 0.378 | |||
| < 60 | 170 (28.5%) | 80 (26.8%) | 90 (30.1%) | |
| ≥ 60 | 427 (71.5%) | 218 (73.2%) | 209 (69.9%) | |
| Pathologic stage | < 0.001 | |||
| I | 108 (18.1%) | 69 (23.1%) | 39 (13.1%) | |
| II | 225 (37.7%) | 120 (40.3%) | 105 (35.1%) | |
| III | 177 (29.6%) | 86 (28.9%) | 91 (30.4%) | |
| IV | 87 (14.6%) | 23 (7.7%) | 64 (21.4%) | |
| T | 0.002 | |||
| T1 | 19 (3.2%) | 11 (3.7%) | 8 (2.7%) | |
| T2 | 105 (17.6%) | 65 (21.8%) | 40 (13.4%) | |
| T3 | 408 (68.3%) | 201 (67.5%) | 207 (69.2%) | |
| T4 | 65 (10.9%) | 21 (7.0%) | 44 (14.7%) | |
| N | < 0.001 | |||
| N0 | 342 (57.3%) | 191 (64.1%) | 151 (50.6%) | |
| N1 | 145 (24.3%) | 71 (23.8%) | 74 (24.7%) | |
| N2 | 110 (18.4%) | 36 (12.1%) | 74 (24.7%) | |
| M | < 0.001 | |||
| M0 | 453 (75.9%) | 249 (83.6%) | 204 (68.2%) | |
| M1 | 85 (14.2%) | 22 (7.4%) | 63 (21.1%) | |
| MX | 59 (9.9%) | 27 (9.0%) | 32 (10.7%) |