Fig. 6

TEXscore-associated miRNAs mediate tumor biological mechanisms. A A corplot displayed the correlations between the TEXscore and top 10 negatively associated miRNAs levels in the TCGA-Pan-Cancer cohort. The coefficient was continuous and was represented using colors from red (negative) to blue (positive). P-values are shown with **, * representing P < 0.01, P < 0.05, respectively. B Top 10 negatively associated miRNAs levels decreased in the high-TEXscore settings. P-values are shown with **** representing P < 0.0001. C GO enrichment analysis of the target genes of top 10 negatively associated miRNAs. Key GO terms are shown ranked by counts. D KEGG enrichment analysis of the target genes of top 10 negatively associated miRNAs. Key KEGG pathways are shown ranked by counts