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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Use of proteomics to identify mechanisms of hepatocellular carcinoma with the CYP2D6*10 polymorphism and identification of ANGPTL6 as a new diagnostic and prognostic biomarker

Fig. 3

Proteomic mechanisms of CYP2D6*10 polymorphisms on susceptibility to HCC. a Volcano plot showing 22 upregulated and 66 downregulated proteins. b Total of 88 DEPs between CC and TT groups of HCC patients shown in heat map. GO enrichment analysis shows up-regulated (c) and down-regulated (d) proteins in the TT group. e Heat-map showing 88 statistically significant DEPs between normal individuals (n = 34) and HCC patients (n = 61). f Expression profiles of the top nine significantly up-regulated DEPs in peritumoral tissues of HCC. g Expression profiles of the top five significantly down-regulated DEPs in peritumoral tissues. Data were shown with mean ± SEM, *P < 0.05, **P < 0.01, ***P < 0.001 (M-U-test). DEPs, differentially expressed proteins; HCC, hepatocellular carcinoma

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Journal of Translational Medicine

ISSN: 1479-5876

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