Fig. 2

The oncogenic effect of COL5A2 and EPHB2 in LUAD cells. A–D Western blot analysis indicated the inhibitory efficiency of COL5A2 siRNA and EPHB2 siRNA in A549 cells and H1299 cells. E–H CCK-8 assay showed the proliferation of A549 cells and H1299 cells treated with COL5A2 siRNA and EPHB2 siRNA. I, J EdU assay revealed the proliferation of A549 cells and H1299 cells with COL5A2 inhibition and EPHB2 inhibition. K, L Transwell assays revealed the migration of A549 cells and H1299 cells treated with COL5A2 siRNA and EPHB2 siRNA. M–P Quantitative statistical results of the number of effects of migration of A549 cells and H1299 cells. Data are shown as the mean ± SD of at least three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001