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Table 2 Clinic characteristics of screening cohort

From: Urinary small extracellular vesicles derived CCL21 mRNA as biomarker linked with pathogenesis for diabetic nephropathy

 

Healthy control (n  =  4)

T2DM (n  =  4)

DN (n  =  4)

Males

2 (50%)

2 (50%)

2 (50%)

Age (years)

31 (25–38)

55 (49–59)

51 (47–53)

BMI (kg/m2)

23.67 (21.68–26.31)

25.50 (20.57–29.73)

25.96 (20.02–32.12)

Total cholesterol (g/L)

–

5.08 (2.93–6.96)

4.66 (4.22–5.15)

Triglyceride (mg/dL)

–

2.14 (1.17–3.34)

2.00 (1.68–2.20)

BUN (mmol/L)

4.9 (4.1–5.5)

7.1 (5.6–8.3)

12.4 (7.5–16.4)**#

SCr (umol/L)

70.5 (61.3–79.3)

81.3 (69.8–91.5)

161.5 (105.5–219.5)*#

UA (umol/L)

310 (294–324)

308 (269–365)

333 (308–375)

Plasma albumin (g/L)

48 (45–51)

42 (38–45)

31 (25–36)**#

eGFR (ml/min/1.73m2)

94 (81.3–112.5)

90 (81.3–101.3)

57.8 (48.9–67.4)**#

Urinary ACR (mg/g)

2.4 (0–8.9)

55 (5–150)

579 (208–707)**##

  1. eGFR has been calculated using the CKD-EPI Creatinine formula (ml/s per 1.73 m2). Values are expressed as median (IQR) (Mann–Whitney U test, *p  <  0.05, **p  <  0.01 compared with healthy controls; #p  <  0.05, ##p  <  0.01 compared with T2DM)
  2. BMI body mass index; BUN blood urea nitrogen; SCr serum creatinine; UA uric acid; eGFR estimated glomerular filtration rate