|
Healthy control (n = 4)
|
T2DM (n = 4)
|
DN (n = 4)
|
---|
Males
|
2 (50%)
|
2 (50%)
|
2 (50%)
|
Age (years)
|
31 (25–38)
|
55 (49–59)
|
51 (47–53)
|
BMI (kg/m2)
|
23.67 (21.68–26.31)
|
25.50 (20.57–29.73)
|
25.96 (20.02–32.12)
|
Total cholesterol (g/L)
|
–
|
5.08 (2.93–6.96)
|
4.66 (4.22–5.15)
|
Triglyceride (mg/dL)
|
–
|
2.14 (1.17–3.34)
|
2.00 (1.68–2.20)
|
BUN (mmol/L)
|
4.9 (4.1–5.5)
|
7.1 (5.6–8.3)
|
12.4 (7.5–16.4)**#
|
SCr (umol/L)
|
70.5 (61.3–79.3)
|
81.3 (69.8–91.5)
|
161.5 (105.5–219.5)*#
|
UA (umol/L)
|
310 (294–324)
|
308 (269–365)
|
333 (308–375)
|
Plasma albumin (g/L)
|
48 (45–51)
|
42 (38–45)
|
31 (25–36)**#
|
eGFR (ml/min/1.73m2)
|
94 (81.3–112.5)
|
90 (81.3–101.3)
|
57.8 (48.9–67.4)**#
|
Urinary ACR (mg/g)
|
2.4 (0–8.9)
|
55 (5–150)
|
579 (208–707)**##
|
- eGFR has been calculated using the CKD-EPI Creatinine formula (ml/s per 1.73 m2). Values are expressed as median (IQR) (Mann–Whitney U test, *p < 0.05, **p < 0.01 compared with healthy controls; #p < 0.05, ##p < 0.01 compared with T2DM)
- BMI body mass index; BUN blood urea nitrogen; SCr serum creatinine; UA uric acid; eGFR estimated glomerular filtration rate