Fig. 5

Features of TIME in different subtypes. A Based on the results of ssGSEA in LGG samples, the difference of enrichment score of each sample changes in IS1, IS2, and IS3, as the heatmap showed. B The difference of enrichment score of each sample changes in IS2 and IS2 shown in the boxplots. C The difference analysis of the abundance of immune cells and the level of the stromal, immune score on IS1, IS2, and IS3. D The difference analysis of the abundance of immune cells and the level of the stromal, immune score on IS2 and IS3. E The different expression levels of ICP genes in IS1, IS2, and IS3. F The different expression levels of ICD-related genes among three subtypes. *** p < 0.001, ** p < 0.01, * p < 0.05, ns: not significant