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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: E3 ubiquitin ligase TRIM29 promotes pancreatic cancer growth and progression via stabilizing Yes-associated protein 1

Fig. 5

YAP1 mediated TRIM29-induced proliferation in pancreatic cancer cells. A western blot showing TRIM29 and YAP1 expression in BxPC-3 cells stably transfected with shTRIM29 in the presence or absence of P-YAP1. BD, EdU and CCK8 assays showed that the reduced proliferation induced by TRIM29 knockdown in BxPC-3 cells was partially abolished by the introduction of P-YAP1 (*p < 0.05). E western blot analysis of TRIM29 and YAP1 protein expression in PANC-1 cells stably transfected with P-TRIM29 in the presence or absence of shYAP1. FH, CCK8 and EdU assays showed that the increased proliferation induced by TRIM29 overexpression in PANC-1 cells was partially abolished by the introduction of shTRIM29

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