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Table 1. 14 candidate predictive biomarkers for PsA

From: Identification of proteins associated with development of psoriatic arthritis in peripheral blood mononuclear cells: a quantitative iTRAQ-based proteomics study

Proteins Name PsA/PsO PsA/HC
Adj.p-value FC Adj.p-value FC
SIRT2 Sirtuin-2 0.008 1.346 0.001 1.648
NAA50 N-alpha-acetyltransferase 50 0.027 1.531 0.001 1.735
ARF6 ADP-ribosylation factor 6 0.027 1.197 0.006 1.391
ADPRHL2 Poly(ADP-ribose) glycohydrolase ARH3 0.032 1.270 0.007 1.650
SF3B6 Splicing factor 3B subunit 6 0.027 1.359 0.008 1.597
SH3KBP1 SH3 domain-containing kinase-binding protein 1 0.049 1.267 0.011 1.466
UBA3 NEDD8-activating enzyme E1 catalytic subunit 0.030 1.254 0.017 1.333
SCP2 Non-specific lipid-transfer protein 0.015 1.225 0.018 1.273
RPS5 Ribosomal protein S5 0.008 0.645 0.024 0.689
NUDT5 ADP-sugar pyrophosphatase 0.030 1.208 0.029 1.317
NCBP1 Nuclear cap-binding protein subunit 1 0.049 1.337 0.030 1.370
SYNE1 Nesprin-1 0.018 1.344 0.035 1.324
NDUFB7 NADH dehydrogenase 1 beta subcomplex subunit 7 0.002 1.511 0.040 1.302
HTATSF1 HIV Tat-specific factor 1 0.018 0.738 0.048 0.787
  1. HC healthy controls, FC fold change