Table 14 Identified scalp stimulation targets for major depression
From: Potential scalp stimulation targets for mental disorders: evidence from neuroimaging studies
Cluster ID | Cluster size | Peak T | Peak coordinates | Brain regions | 10–20 EEG system locations | Acupoint locations | Functions | ||
|---|---|---|---|---|---|---|---|---|---|
x | y | z | |||||||
MD-1 | 858 | 9.54 | − 46 | 26 | − 10 | L IFG/OrbIFG/TriIFG/OperIFG/MFG/PreCG/STG | 0.5 cm posterior and inferior to F7 | 0.6 cun anterior and inferior to GB 6 | Language processing and comprehension, emotional recognition |
MD-2 | 271 | 8.36 | − 46 | − 66 | 0 | L MOG/MTG/ITG | 1.5 cm posterior and inferior to T5 | 0.3 cun posterior and inferior to GB 10 | Tracking visual motion patterns, feature-based attention, orientation-selective attention, visual memory recognition, spatial working memory, inferential reasoning, visual mental imagery |
MD-3 | 351 | 7.17 | − 2 | 58 | 20 | L MedFG/SupMFG/OrbMFG/SFG | Midpoint of Fp1 and Fp2 | 0.3 cun posterior to GV 24 | Working memory, episodic memory, multiple-task coordination, decision making |
MD-4 | 349 | 8.36 | − 2 | 10 | 52 | L MedFG/SMA | 0.5 cm anterior to Cz | 0.1 cun anterior to GV 21 | Motor sequencing/planning/learning/imagery, language processing, working memory, episodic long-term memory, visuospatial attention, visuomotor attention, executive control of behavior, processing emotions and self-reflections in decision making |
MD-5 | 227 | 6.58 | 2 | − 54 | 24 | R PCu/PoCG | Pz | 0.1 cun anterior to GV 19 | Self-consciousness, attention, episodic memory retrieval, working memory, conscious perception, response inhibition, visuospatial mental operations |
MD-6 | 769 | 8.95 | 36 | 28 | 2 | R IFG/OrbIFG/TriIFG/OperIFG/MFG/PreCG | 0.5Â cm posterior and inferior to F8 | 0.3 cun inferior to GB 5 | Semantic decision tasks (determining whether a word represents an abstract or a concrete entity), generation tasks (generating a verb associated with a noun), semantic retrieval/working memory processes |
MD-7 | 236 | 7.17 | 50 | − 58 | 24 | R STG/MTG/IPL/SMG/AG | Midpoint of P4 and O2 | Midpoint of GB 10 and GB 18 | Reading, spatial focusing of attention, theory of mind, executive control of behavior |
MD-8 | 441 | 7.76 | 42 | − 78 | − 6 | R IOG/MOG/STG/ITG/MTG | 2 cm anterior and inferior to O2 | 0.6 cun posterior to GB 10 | Visuo-spatial information processing, visual memory recognition, spatial working memory, visual mental imagery |