Age (y)
|
50.719 (10.638)
|
51.051 (10.433)
|
50.449 (10.808)
|
0.295
|
Height (cm)
|
167.954 (9.065)
|
167.734 (6.428)
|
168.134 (10.753)
|
0.052
|
Weight (kg)
|
64.628 (11.304)
|
63.404 (10.889)
|
65.628 (11.548)
|
0.004
|
Body Mass Index
|
22.782 (3.574)
|
22.539 (3.529)
|
22.98 (3.602)
|
0.018
|
Preoperative LOS (d)
|
11 (2–26)
|
14 (4–28)
|
8 (2–23)
|
0.001
|
Diagnosis of AKI
|
No AKI
| |
350.0 (100.0%)
|
/
| |
Stage 1 AKI
| |
/
|
177.0 (41.163%)
| |
Stage 2 AKI
| |
/
|
63.0 (14.651%)
| |
Stage 3 AKI
| |
/
|
190.0 (44.186%)
| |
Stage 3 AKI requring CRRT
| |
/
|
159.0 (36.977%)
| |
AKI diagnosis during POD1
| |
/
|
288 (66.977%)
| |
Preoperative renal function
|
CKD (n)
|
121.0 (15.513%)
|
49.0 (14.0%)
|
72.0 (16.744%)
|
0.34
|
AKI (n)
|
172.0 (22.051%)
|
67.0 (19.143%)
|
105.0 (24.419%)
|
0.093
|
HRS (n)
|
33.0 (4.231%)
|
8.0 (2.286%)
|
25.0 (5.814%)
|
0.024
|
SCr (μmol/L)
|
91.777 (70.334)
|
92.388 (68.852)
|
91.28 (71.593)
|
0.047
|
BUN (mmol/L)
|
6.846 (5.823)
|
6.56 (5.218)
|
7.078 (6.268)
|
0.985
|
eGFR (ml/(min*1.732))
|
95.029 (32.145)
|
93.749 (29.966)
|
96.07 (33.813)
|
0.127
|
SCr_Mean (μmol/L)
|
79.343 (71.641)
|
75.837 (65.256)
|
82.197 (76.402)
|
0.917
|
Use of CRRT (n)
|
94.0 (12.051%)
|
24.0 (6.857%)
|
70.0 (16.279%)
|
< 0.001
|
Frequency of CRRT (times)
|
2.567 (10.727)
|
1.351 (8.312)
|
3.556 (12.269)
|
< 0.001
|
Preoperative laboratory values
|
HCT
|
0.299 (0.076)
|
0.312 (0.08)
|
0.288 (0.07)
|
< 0.001
|
PLT(109/L)
|
96.026 (79.4)
|
116.597 (95.149)
|
79.281 (58.79)
|
< 0.001
|
ALT (U/L)
|
126.282 (399.834)
|
90.349 (235.856)
|
155.53 (493.081)
|
0.004
|
AST (U/L)
|
172.242 (538.996)
|
148.429 (369.227)
|
191.626 (644.817)
|
< 0.001
|
TBIL (μmol/L)
|
250.278 (249.713)
|
172.311 (217.596)
|
313.739 (256.351)
|
< 0.001
|
DBIL (μmol/L)
|
159.74 (168.516)
|
116.107 (152.227)
|
195.256 (172.907)
|
< 0.001
|
IBIL (μmol/L)
|
90.537 (96.523)
|
56.204 (72.764)
|
118.483 (104.24)
|
< 0.001
|
ALB (g/L)
|
35.668 (4.906)
|
36.212 (5.283)
|
35.225 (4.535)
|
0.023
|
PT (s)
|
25.16 (13.483)
|
21.115 (9.851)
|
28.452 (15.064)
|
< 0.001
|
APTT (s)
|
54.653 (20.923)
|
49.183 (16.041)
|
59.105 (23.267)
|
< 0.001
|
FIB (g/L)
|
1.982 (1.422)
|
2.357 (1.372)
|
1.676 (1.39)
|
< 0.001
|
INR
|
2.339 (1.574)
|
1.912 (1.397)
|
2.686 (1.625)
|
< 0.001
|
Etiology of liver
|
Hepatitis B (n)
|
577.0 (73.974%)
|
257.0 (73.429%)
|
320.0 (74.419%)
|
0.817
|
Hepatitis C (n)
|
17.0 (2.179%)
|
11.0 (3.143%)
|
6.0 (1.395%)
|
0.157
|
Dual infection (n)
|
9.0 (1.154%)
|
5.0 (1.429%)
|
4.0 (0.93%)
|
0.756
|
Hepatic Malignancy (n)
|
312.0 (40.0%)
|
190.0 (54.286%)
|
122.0 (28.372%)
|
< 0.001
|
Cirrhosis (n)
|
623.0 (79.872%)
|
292.0 (83.429%)
|
331.0 (76.977%)
|
0.032
|
Preoperative complications
|
MELD score
|
24 (22–35)
|
22(22–29)
|
30 (22–38)
|
< 0.001
|
Portal hypertension (n)
|
407.0 (52.179%)
|
192.0 (54.857%)
|
215.0 (50.0%)
|
0.201
|
Ascites (n)
|
321.0 (41.154%)
|
142.0 (40.571%)
|
179.0 (41.628%)
|
0.822
|
HE (n)
|
180.0 (23.077%)
|
41.0 (11.714%)
|
139.0 (32.326%)
|
< 0.001
|
Plasmapheresis (n)
|
7.0 (0.897%)
|
2.0 (0.571%)
|
5.0 (1.163%)
|
0.625
|
HPS (n)
|
4.0 (0.513%)
|
1.0 (0.286%)
|
3.0 (0.698%)
|
0.766
|
ARDS (n)
|
7.0 (0.897%)
|
3.0 (0.857%)
|
4.0 (0.93%)
|
0.784
|
ALI (n)
|
0.0 (0.0%)
|
0.0 (0.0%)
|
0.0 (0.0%)
|
1
|
MV (n)
|
49.0 (6.282%)
|
9.0 (2.571%)
|
40.0 (9.302%)
|
< 0.001
|
ICU stay (n)
|
439.0 (56.282%)
|
164.0 (46.857%)
|
275.0 (63.953%)
|
< 0.001
|
Hypernatremia (n)
|
44.0 (5.641%)
|
10.0 (2.857%)
|
34.0 (7.907%)
|
0.004
|
Metabolic acidosis (n)
|
336.0 (43.077%)
|
144.0 (41.143%)
|
192.0 (44.651%)
|
0.362
|
Donor characteristics
|
Donor age (y)
|
39.191 (13.966)
|
38.894 (14.392)
|
39.433 (13.621)
|
0.755
|
Donor BMI
|
22.578 (3.199)
|
22.336 (3.185)
|
22.779 (3.201)
|
0.074
|
ABO incompatibility (n)
|
120.0 (15.385%)
|
38.0 (10.857%)
|
82.0 (19.07%)
|
0.002
|
Donor Type
| | | |
0.248
|
DBD (n)
|
448 (57.436%)
|
212 (60.571%)
|
236 (54.884%)
| |
DCD (n)
|
324 (41.538%)
|
134 (38.286%)
|
190 (44.186%)
| |
DBCD (n)
|
8 (1.026%)
|
4 (1.143%)
|
4 (0.93%)
| |
Steatosis of donor liver
| | | |
0.002
|
Steatosis grade 0 (n)
|
529 (67.821%)
|
260.0 (74.286%)
|
269 (62.558%)
| |
Steatosis grade 1 (n)
|
170 (21.795%)
|
62.0 (17.714%)
|
108 (25.116%)
| |
Steatosis grade 2 (n)
|
35 (4.487%)
|
9.0 (2.571%)
|
26 (6.047%)
| |
Steatosis grade 3 (n)
|
1 (0.128%)
|
0.0 (0.0%)
|
1 (0.233%)
| |
Steatosis grade ≥ 1
|
206.0 (26.41%)
|
71.0 (20.286%)
|
135.0 (31.395%)
|
0.001
|
Steatosis grade ≥ 2
|
36.0 (4.615%)
|
9.0 (2.571%)
|
27.0 (6.279%)
|
0.022
|
Lack of pathology assesment (n)
|
45 (5.769%)
|
19 (5.429%)
|
26 (6.046%)
|
0.721
|
Surgery characteristics
|
Time of surgery (min)
|
442.713 (92.854)
|
425.297 (87.949)
|
456.888 (94.418)
|
< 0.001
|
Time under anesthesia (min)
|
538.888 (97.864)
|
519.56 (92.679)
|
554.621 (99.251)
|
< 0.001
|
Recipient warm ischemic time (min)
|
46.45 (12.035)
|
45.919 (12.183)
|
46.883 (11.909)
|
0.088
|
Cold ischemic time (h)
|
6.255 (1.358)
|
6.226 (1.393)
|
6.278 (1.329)
|
0.476
|
Surgical technique
| | | |
0.304
|
Piggyback (n)
|
713 (91.41%)
|
317 (90.571%)
|
396 (92.093%)
| |
Split liver (n)
|
36 (4.615%)
|
15 (4.286%)
|
21 (4.884%)
| |
Standard (n)
|
31 (3.974%)
|
18 (5.143%)
|
13 (3.023%)
| |
Intraoperative fluid and transfusion
|
Crystalloid (ml)
|
2618.423 (2240.489)
|
2775.575 (2366.817)
|
2490.944 (2126.798)
|
0.094
|
Colloid (ml)
|
124.26 (427.879)
|
153.448 (424.742)
|
100.583 (429.443)
|
0.006
|
Albumin (ml)
|
218.295 (116.74)
|
222.629 (111.083)
|
214.779 (121.15)
|
0.483
|
Transfusion
|
RBC (ml)
|
1500.39 (1318.45)
|
1279.989 (1333.507)
|
1679.177 (1280.024)
|
< 0.001
|
Plasma (ml)
|
1862.806 (1613.71)
|
1725.862 (1376.393)
|
1973.893 (1777.029)
|
0.063
|
Cryoprecipitate (U)
|
30.276 (15.83)
|
27.359 (14.9)
|
32.653 (16.182)
|
< 0.001
|
EBL (ml)
|
2051.489 (2027.519)
|
1679.857 (1890.832)
|
2354.685 (2086.165)
|
< 0.001
|
Urine output (ml·kg−1·h−1)
|
3.104 (2.146)
|
3.708 (2.219)
|
2.613 (1.954)
|
< 0.001
|
Ascites removal (ml)
|
959.665 (1889.757)
|
947.011 (1997.938)
|
969.93 (1799.531)
|
0.196
|
Intraoperative medication
|
rFVIIa (mg)
|
0.346 (1.127)
|
0.211 (1.03)
|
0.455 (1.19)
|
< 0.001
|
Prothrombin complex concentrate (IU)
|
587.692 (433.693)
|
554.857 (434.497)
|
614.419 (431.7)
|
0.043
|
Fibrinogen (g)
|
0.404 (1.293)
|
0.342 (0.735)
|
0.453 (1.609)
|
0.567
|
Terlipressin (mg)
|
0.322 (0.551)
|
0.195 (0.447)
|
0.426 (0.604)
|
< 0.001
|
Norepinephrine, bolus (mg)
|
0.008 (0.022)
|
0.006 (0.018)
|
0.009 (0.024)
|
0.353
|
Epinephrine, bolus (mg)
|
0.028 (0.299)
|
0.011 (0.161)
|
0.042 (0.376)
|
0.785
|
Dopamine, bolus (mg)
|
12.0 (1.538%)
|
4.0 (1.143%)
|
8.0 (1.86%)
|
0.874
|
Bicarbonate (ml)
|
127.006 (234.266)
|
89.429 (221.225)
|
157.593 (240.316)
|
< 0.001
|
Use of norepinephrine, continuous (n)
|
649.0 (83.205%)
|
301.0 (86.0%)
|
348.0 (80.93%)
|
0.074
|
Use of epinephrine, continuous (n)
|
553.0 (70.897%)
|
250.0 (71.429%)
|
303.0 (70.465%)
|
0.829
|
Use of dopamine, continuous (n)
|
245.0 (31.41%)
|
106.0 (30.286%)
|
139.0 (32.326%)
|
0.594
|
Use of aramine (n)
|
34.0 (4.359%)
|
7.0 (2.0%)
|
27.0(6.279%)
|
0.006
|
Intraoperative incident
|
Cardiac arrest (n)
|
21.0 (2.692%)
|
3.0 (0.857%)
|
18.0(4.186%)
|
0.008
|
Acidosis (n)
|
322.0 (41.282%)
|
133.0 (38.0%)
|
189.0 (43.953%)
|
0.108
|
Hypotension (n)
|
649.0 (83.205%)
|
298.0 (85.143%)
|
351.0 (81.628%)
|
0.226
|