Fig. 7
From: CYB561D2 up-regulation activates STAT3 to induce immunosuppression and aggression in gliomas
STAT3 mediates the effects of CYB561D2 in in vivo mouse model. A Kaplan–Meier survival curves of nude mice bearing intracranial gliomas infected with control, CYB561D2 or CYB561D2 + DN-STAT3. B Western blot and its quantification, C showing the protein levels of CYB561D2, PD-L1, CCL2 and TDO2 in intracranial tumor tissues. D Immunohistochemistry showing CYB561D2, PD-L1, MMP2 and Ki-67 in intracranial tumor tissues. E Working model. For all, **P < 0.01; ***P < 0.001